| Accent TherapeuticsLexington, MA · under 50 | Jennifer CastroDirector of Translational and Discovery Biology | Small-molecule inhibitors of RNA-modifying enzymes. Enzyme activity and inhibition assays are the daily work, and the seat is confirmed on the company's own listings. |
| Accutar BiotechCranbury, NJ · under 50 | Jessie Jie SuDirector, Discovery Biology | Computation-led small molecules and degraders with a fresh 2026 partnership. Binding, enzyme and protein work in a team that cannot staff all three. |
| Aktis OncologyBoston, MA · 50 to 150 | Dasa LipovsekVP and Head of Lead Discovery | Miniprotein binders for radiopharmaceuticals. Every candidate needs affinity and kinetics, and the seat is named on the company site. |
| CugeneWaltham, MA · under 50 | Lingyun RuiHead of Protein Sciences | Engineered cytokines and masked bispecifics. Receptor selectivity is a binding-assay question, asked continuously, by a team of about fifteen. |
| Delphia TherapeuticsCambridge, MA · under 50 | Christopher QuinnDirector of Biochemistry | Preclinical oncology with in-house biochemistry at about thirty people. The textbook profile for outsourced assay development. |
| DEM BioPharmaCambridge, MA · under 50 | Loise Francisco-AndersonHead of Biology | Myeloid and macrophage checkpoint biology, funded and hiring. Protein reagents and binding characterization sit under the head of biology. |
| Generate BiomedicinesSomerville, MA · 150 plus | Adam RootVP and Head of Protein Sciences | Generative protein design at scale. A large in-house group that still buys expression, purification and orthogonal characterization when design cycles outrun capacity. |
| Keros TherapeuticsLexington, MA · 50 to 150 | Rosa GrenhaDirector, Protein Biochemistry | Ligand biology in the TGF-beta family. A named protein biochemistry seat with a large-pharma protein sciences background. |
| ModeX TherapeuticsWeston, MA · 50 to 150 | Hao ChenDirector, Protein Sciences | Multispecific antibodies with an in-house protein sciences group that is recruiting. Title as carried on the company's own people page. |
| MOMA TherapeuticsCambridge, MA · about 50 | Michael MorrisonVP, Biochemistry and Biophysics | Mechanism-based discovery on enzymes that move. Confirmed on the company team page, and on record as a user of outsourced discovery services. |
| Rocket PharmaceuticalsCranbury, NJ · 150 plus | Hong LiDirector of Assay Development | Gene therapy with a standing assay development function. The right seat; the name is directory-sourced, so confirm before approach. |
| Scholar RockCambridge, MA · 150 plus | Adam FogelSenior Director, Discovery Biology | Growth factor biology with a discovery group that has an assay development pedigree. Confirmed in role. |
| Souffle TherapeuticsWatertown, MA · 50 to 150 | John YoonDiscovery Biology | Muscle-targeted siRNA conjugates. Binding and characterization work on the conjugate side; a published team contact rather than a confirmed title. |
| Synolo TherapeuticsCambridge, MA · under 50 | Monica MenzenskiHead of Protein Science | Computational protein design and multi-specific biologics at under twenty people. New in the seat, which is when vendor lists get rebuilt. |
| Tango TherapeuticsBoston, MA · 50 to 150 | William MallenderVP, Biochemistry | Precision oncology. Biochemistry leadership owns assay development here, with a large-pharma background in the seat. |
| VidaVinciWatertown, MA · under 50 | Julie DooleyDirector, Biochemistry and Biophysics | A small, funded discovery team with no public pipeline yet. Structurally short of internal capacity, which is the point. |
| Voyager TherapeuticsLexington, MA · 50 to 150 | Richelle SopkoDirector of Protein Science, Non-Viral Therapeutics | Capsid and non-viral delivery. The seat sits over exactly the protein work an outside lab supplies, in a group that is hiring. |